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Italian/Brazilian pianist, clavichordist, harpsichordist and organist, Marco Orsini-Brescia  began his piano studies with his mother, Denise Orsini, pursuing them with Clotilde Lobo de Rezende,  Sergio Magnani and Vera Nardelli. He went on to win the first prize in the 10th National Piano Competition Arnaldo Estrella and the prize for ‘best accompanist’ at the 8th National String Competition Pro-Música, both in Brazil. In 2000, he received a scholarship to the renowned international piano course of the Escuela Superior de Música Reina Sofia, given in Santander by Russel Sherman. The following year, Orsini-Brescia took part in the Daroca International Early Music Course, also in Spain, under the guidance of José Luis González Uriol, and became also increasingly interested in early keyboard instruments and repertoire.

In 2013, Marco Orsini-Brescia completed his Master’s degree in Early Music / Historic Organ Performance at the Escola Superior de Música de Catalunya / Universitat Autònoma de Barcelona under the guidance of Javier Artigas and awarding the prestigious matrícula de honor. In that same year he concluded his joint PhD studies in Musicology at the universities Paris IV–Sorbonne and NOVA de Lisboa, under the supervision of Frédéric Billiet and David Cranmer. His thesis was awarded the maximum grade, très honorable à l’unanimité. He also holds a Master's degree in Art History from the Université Paris IV–Sorbonne and a Bachelor of Architecture degree from the Universidade Federal de Minas Gerais. 

Orsini-Brescia has been invited to perform in the most distinguished venues, international festivals and concert series in Italy, Spain, Portugal, France, England, Northern Ireland, Switzerland, Germany, Hungary, Slovakia, Poland, Brazil, Peru, and Panama. Since 2006, he is part of an acclaimed duo with his wife, soprano Rosana Orsini, with whom he recorded the album 'Angels and Mermaids: religious Music in Oporto and Santiago de Compostela (18th / 19th century)' (Arkhé Music, Portugal, 2016). His solo album 'Zipoli in Diamantina: complete organ works' (Paraty, France, 2020) has been largely praised by international specialised musical magazines (Diapason, Early MusicResMusica, Scherzo, Journal für die Orgel, Orgelnieuws, Rondo) and was broadcasted by the Bayerischer Rundfunk, Germany.

Orsini-Brescia is currently an integrated reseracher at CESEM - Centro de Estudos de Sociologia e Estética Musical / Universidade NOVA de Lisboa, Portugal, where he is vice-coordinator of the group "Music in the Modern Period".

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